Archiving and Distribution
Keeping live mice on shelf for extended periods is not only costly, it also bears the risk of loosing biologically relevant phenotypes due to genetic drift or disease, and it is not desirble for animal welfare reasons. Mouse repositories therefore preserve scientifically valuable mouse models and distribute them to upon request to the biomedical research community.
EMMA - The European Mouse Mutant Archive is the leading mouse repository in Europe and important partner in the global network of mouse archives. EMMA offers archiving and distribution of mouse models under highest quality standards and access to the strain data in the EMMA resource database. An additional specialized service of EMMA is the generation of germ-free (axenic) mice.
Over the last years the demand for the services of EMMA has seen a steep increase. In the context of the Infrafrontier Project the existing national EMMA nodes will therefore be upgraded, and new national nodes will be integrated into the EMMA network.
The Infrafrontier consortium comprises existing and potential EMMA partners:
Existing Partners:
- Consiglio Nazionale delle Ricerche (CNR-IBC), Prof. Glauco Tocchini-Valentini, Monterotondo/Rome, Italy
- CNRS Institute de Transgenose (INTRAGENE), Dr. Yann Hérault, Orléans, France
- MRC Mammalian Genetics Unit (MRC-MGU), Prof. Steve Brown, Harwell, UK
- Karolinska Institute (KI), Prof. Urban Lendahl, Stockholm, Sweden
- Fundação Calouste Gulbenkian (FCG-IGC), Dr. Jocelyne Demengeot, Oeiras, Portugal
- Helmholtz Zentrum München - German Research Center for Environmental Health, GmbH, Prof. Martin Hrabé de Angelis (Infrafrontier Coordinator), Neuherberg/München, Germany
- European Molecular Biology Laboratory (EMBL-EBI), Dr. Ewan Birney, Hinxton, UK
- Centre Européen de Recherche en Biologie et en Médecine GIE (CERBM-GIE), Prof. Yann Hérault, Illkirch/Strasbourg, France
- Genome Research Limited (Sanger), Prof. Karen Steel, Hinxton, UK
- Centro Nacional de Biotecnología (CNB-CSIC), Dr. Lluís Montoliu, Madrid, Spain
- Biomedical Sciences Research Center Alexander Fleming (Fleming), Prof. George Kollias, Vari/Athens, Greece
Potential Partners:
- Czech Centre for Phenogenomics (BIOCEV) c.z.p.o., Dr. Radislav Sedlacek, Czech Republic
- University of Veterinary Medicine Vienna, Biomodels Austria (Biat), Prof. Thomas Rülicke, Vienna, Austria
- University of Oulu (UOULU), Prof. Taina Pihlajaniemi, Oulu, Finland
- University of Copenhagen (KU-TCF), Prof. Cord Brakebusch, Copenhagen, Denmark
Last revision December 2010