INFRACoMP

 

InfraCoMP objectives

InfraCoMP's main objective is to coordinate collaboration between the INFRAFRONTIER Research Infrastructure and the  International Mouse Phenotyping Consortium (IMPC). To this end, InfraCoMP organises regular workshops that address the central issues that need to be resolved to ensure a fruitful cooperation between the two initiatives, that minimises redundancy, maximises mutual benefit and leverages the expertise and infrastructure capacity.

Key InfraCoMP topics are:

  • Mouse Phenotyping
  • Mouse Production Archiving and Distribution
  • Access to Phenotyping
  • Data Community Engagement

InfraCoMP is funded by the EC FP7 Capacities Specific Programme, Grant Agreement number 284501.

InfraCoMP partners

CERBM-GIE, Strasbourg, France

CNR-Monterotondo, Rome, Italy

EMBL-EBI, Hinxton, United Kingdom

Helmholtz Zentrum München, Munich, Germany

Institute of Molecular Genetics ASCR, Prague, Czech Republic

MRC Harwell, Oxfordshire, United Kingdom

Sanger Institute, Hinxton, United Kingdom

Toronto Centre for Phenogenomics, Toronto, Canada

Universitat Autonoma de Barcelona, Barcelona, Spain

InfraCoMP work packages

Work package WP1 - Management

Work package WP2 - Coordination INFRAFRONTIER-IMPC

Work package WP3 - Mouse Phenotyping

Work package WP4 - Mouse Production, Cryopreservation and Distribution

Work package WP5 - Access to Phenotyping Data

Work package WP6 - Community Engagement

 

InfraCoMP Kick-Off Meeting

InfraCoMP was launched in November 2011, in Munich, Germany attracting international attention in a Kick-Off meeting, with over 80 participants, representing 14 nations from 4 continents.

 

InfraCoMP Workshop on IMPC Embryonic Lethal Phenotyping

April 2012, London, UK - 'InfraCoMP Workshop on IMPC Embryonic Lethal Screening', with the objective of agreeing in a consensus strategy for embryonic phenotyping.

Read also:

'Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening' PMID: 23519032

INFRAFRONTIER / IMPC Korea Meeting

September 2012, Jeju, Korea - 'INFRAFRONTIER IMPC Korea meeting' with the objective of showcasing Asia's important position in the global effort to functionally annotate the entire mammalian genome and provide information on the activities of mouse phenotyping in Asia and its integration with both INFRAFRONTIER and IMPC efforts.

 Korea meeting, Jeju, September 2012

InfraCoMP: INFRAFRONTIER/IMPC Korea Meeting, 2012 - Group Photo

 

INFRAFRONTIER / IMPC / IKMC Rome Meeting

December 2013, Rome, Italy - 'INFRAFRONTIER, IMPC & IKMC meeting', with the objective to discuss how researchers from different scientific fields and from industry can benefit from the large-scale mouse genomics initiatives INFRAFRONTIER, the IMPC and the IKMC, and to obtain feedback from the research community on future needs and improvements. The meeting counted with the participation of more than 200 participants, from all over the world.

The meeting was funded through the EC-funded projects InfraCoMP and EUCOMTOOLS, the Italian National Research Council (CNR) generously provided the meeting venue.

 

INFRAFRONTIER / IMPC San Francisco Phenotyping Workshop

March 2014, San Francisco, USA - 'INFRAFRONTIER IMPC Phenotyping Workshop', with the objective of accessing the progress of the tests and phenotype detection, as well as to discuss the tests implementation for IMPC Phase II.

 

INFRAFRONTIER / IMPC Mouse Repository Workshop

May 2014, Munich, Germany - 'INFRAFRONTIER / IMPC Workshop - Promoting the international exchange of mouse mutant resources', whose main objective was to simplify the international exchange of mouse mutant resources and to define the procedural changes required to achieve this goal.

The workshop was targeted at the directors of major mouse repositories, IP and technology transfer experts, representatives of scientific journals and funders and was attended by 70 participants.

Read the meeting report: International Society for Transgenic Technologies Blog (Lluis Montoliu)

Read more about: Nature Editorial: Still much to learn about mice. (Allison Abbot)

INFRAFRONTIER/IMPC  meeting, May 2014

INFRAFRONTIER/IMPC Workshop: Promoting the international exchange of mouse mutant resources, Munich, Germany, May 2014

 

INFRAFRONTIER / IMPC Statistical Technical Group Meeting

July, 2014, Cambridge, UK – The INFRAFRONTIER / IMPC Statistical Technical Group meeting highlighted the importance of statistical analysis to accurately functionally annotate the entire mammalian genome and provided information on current knowledge. The resulting discussions helped shaping the active research into the data analysis issues surrounding high throughput mouse phenotyping.
The meeting counted with the presence of more than 20 participants representing 14 institutes from diverse fields such as statistics, bio-informatics, informatics and biology. Through several presentations and multiple breakout group discussions the INFRAFRONTIER / IMPC Statistical Technical Group Meeting provided a unique opportunity to share knowledge and discuss the issues and potential solutions for the large-scale analysis of data from high throughput phenotyping

 

The results of the workshops are documented in meeting reports and are publicised by different communications means. InfraCoMP will address the specific requirements of an international collaboration of INFRAFRONTIER and IMPC. A successful collaboration between INFRAFRONTIER and the IMPC, catalysed by InfraCoMP, will move forward the entire research field of mouse models for human diseases.