IPAD-MD
IPAD-MD project (Research Infrastructure for Phenotyping, Arching and Distribution of Mouse Diseases Models) addresses the global cooperation and coordination between INFRAFRONTIER and complementary research infrastructures world-wide, contributing to the global effort of IMPC. IPAD-MD will focus on key stakeholder involvement.
IPAD-MD organizes a series of workshops aiming at:
- Improving access to common INFRAFRONTIER and IMPC resources
- Aligning scientific strategy with international research agendas
- Engaging key stakeholders to improve INFRAFRONTIER and IMPC resources and services
- Coordinating globally the development of innovative technology solutions
Topic I. Global Access to Common Resources
Keywords: MTAs, IP and licensing models, repositories sustainable funding, material shipping issues, standards & nomenclature
Topic II. Key Stakeholder Engagement
Keywords: Resource usability, (priorisation) mouse disease models, visibility of resources and services
Topic III. Innovative Technology Solutions
Keywords: (optimisation) existing pipelines, common standards, reliability and interoperability, big data & data services
Cross-cutting themes
Animal welfare
Outreach to Africa
Communications & Dissemination
2015: Kick-Off meeting, July 21-22, Munich, Germany
2016: Industry & Innovation Worskhop, 28-29 June, Munich, Germany
Agenda & List of Participants (17.06.2016)
Exhibition area - Floor plan (20.06.2016)
Industry & Innovation Workshop Report (D2.1; 28.06.2016)
Literature collection to support the panel discussions
Panel 1: Impact of CRISPR technology on repositories, IT & animal welfare
Dow. 2015. Modeling Disease In Vivo with CRISPR/Cas9. PMID: 26432018
Hsu et al. 2014. Development and applications of CRISPR-Cas9 for genome engineering.PMID: 24906146
Ledford. 2015. CRISPR, the disruptor. PMID: 26040877
Panel 2: Impact of rodents as model of human diseases
Collins & Tabak. 2014. NIH plans to enhance reproducibitlity. PMID: 24482835
Ioannidis JPA. 2014. How to make more published research true PMID: 25334033
Macleod et al 2014. Biomedical research: increasing value, reducing waste PMID: 24411643
Perrin. 2014. Make mouse studies work. PMID: 24678540
Vandamme. 2015. Rodent models for human diseases. PMID: 25823811
2015
Standards & Technology Expert Group Meeting - Phenotyping, September 14-15, Seoul, Korea & Archiving, November 18, Rome, Italy
Meeting report (D6.1, 11.12.2015)
Data & Resources Expert Group Meeting, October 27-28, Hinxton, UK
Meeting report (D7.1, 01.12.2015)
2016
Standards & Technology Expert Group Meeting (WP6) : 'Genome Editing Workshop' at IMPC - INFRAFRONTIER Strasbourg meeting, 20-22 April 2016
Meeting report (D6.2, 20.04.2016)
Data & Resources Expert Group Meeting (WP7): Improving Curation and Annotation Tooling for Animal Models of Rare Disease, 08-09 December 2016, Freising, Germany
Workshop goals
- Facilitate communication between curators that have an interest in annotating animal models of human disease
- Discuss the strengths and weaknesses of curatorial resources (ontologies, tools, etc)
- Investigate synergies between groups to accelerate annotation of rare disease models
Partners
INFRAFRONTIER GmbH, Munich, Germany
MRC Harwell, Oxfordshire, United Kingdom
EMBL-EBI, Hinxton, United Kingdom
International Stakeholders
African Center for System Genetics (ASGEN)
Australian Phenomics Network (APN)
Eric Marcotte, Canadian Institutes of Health Research, Institute of Genetics (CIHR); Chair Executive Committee International Human Epigenome Consortium (IHEC)
International Centre for Genetic Engineering and Biothecnology (ICGEB)
International Mouse Phenotyping Consortium (IMPC)
Paul Lasko, International Rare Diseases Research Consortium (IRDiRC)
Korean Mouse Phenoytping Center (KMPC)
Mouse Biology Programm, University California Davis (UCD)
Work package 1 - Management
D1.1: Minutes Kick-Off Meeting (27.08.2015)
Work package 2 - Coordination & Workshop organisation
D2.1: Report on Stakeholder Engagement Meeting - Industry & Innovation Workshop (28.06.2016)
Work package 3 - Engagement with Funders & Policy
D3.1: Survey on European and International Research Agendas (22.12.2015)
Work package 4 - Engagement with Users & Industry
Work package 5 - Engagement with Patient Organisations
D5.1: Survey on Patient Organization Research Agendas
Work package 6 - Implementing Standards & Technology
D6.1: Report on Standards & Technology Expert Group Meeting (11.12.2015)
D6.2: Report on Standards & Technology Expert Group Meeting (20.04.2016)
Work package 7 - Access to Data & Standards
D7.1: Report on Data & Resources Expert Group Meeting (21.12.2015)
D7.2: Report on Data & Resources Expert Group Meeting (08.12.2016)
Work package 8 - Animal Welfare
IPAD-MD has received funding from European Union's Horizon 2020 research and innovation programme under Grant Agreement number 653961.
