News & Events

Upcoming INFRAFRONTIER training courses

6 Mar 2017

Partners of the INFRAFRONTIER Research Infrastructure offer unique training opportunities in mouse phenogenomics, genome editing and cryopreservation technologies.

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Mouse surgery workshop at UPMC Paris, France

2 Mar 2017

The Jackson Laboratory is delivering a hands-on mouse surgery workshop at UPMC in Paris, France.

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INFRAFRONTIER open call - Disease model development and systemic phenotyping

20 Dec 2016

Proposal submission to proposals@infrafrontier.eu by 15 February 2017

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Anatomical Bases of Mouse Multimodal Imaging Course,16-20 January 2017

21 Oct 2016

The preliminary programme for the Anatomical Bases of Mouse Multimodal Imaging Course, which will be held at the Czech Centre for Phenogenomics (CCP) has been announced.

This 5 day hands-on course will be led by Jesús Ruberte and Marc Navarro, authors of the textbook 'Morphological Mouse Phenotyping: Anatomy, Histology and Imaging'.

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CORBEL launches 1st Open Call for research projects

5 Oct 2016

CORBEL – Coordinated Research Infrastructures Building Enduring Life-science services – is an EC Horizon2020 project uniting 11 Biological and Medical Science Research Infrastructures (RIs). In CORBEL, the participating RIs expand their cooperation in order to harmonise researchers’ access to their cutting-edge technologies and services by establishing a sustainable platform of aligned services that will enable faster admission to and a wider portfolio of technologies and services to boost research projects.

 

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IMPC study shows that genes essential to life are enriched in human and mouse

14 Sep 2016

Roughly a third of all genes in the mammalian genome are essential for life. A new article in Nature, from an international, multi-institutional research team including many INFRAFRONTIER partners, describes the large-scale discovery of those genes and how it will impact understanding of mammalian development and human disease.

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Upcoming Training Courses in Mouse Phenogenomics at phenomin

12 Sep 2016

Strasbourg, France, 2016 November 09th-10th

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INFRAFRONTIER Rates Changing as of 01 August 2016

25 Jul 2016

INFRAFRONTIER service charges will be changing as of 01 August 2016. New pricing will be posted and take effect as of 01 August 2016.

We will honor previously quoted rates for registrations of interest (ROI) and projects with ongoing services initiated prior to 01 August. Projects initiated after 01 August will be quoted and billed with the new rates.

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INFRAFRONTIER Industry & Innovation Workshop

6 Jul 2016

On 28 and 29 June the INFRAFRONTIER Industry & Innovation Workshop took place in Munich. 88 participants from Europe, North America, Asia and Australia, among them 23 representatives from industry, discussed technological innovations, how biopharma uses mammalian models in drug discovery and how the resources and services provided by the INFRAFRONTIER Research Infrastructure and the International Mouse Phenotyping Consortium (IMPC) can support translational research.

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INFRAFRONTIER Article in Mammalian Genome

16 Jun 2016

The next issue of the Journal 'Mammalian Genome' will be dedicated to the study of ageing and age-related diseases. It contains an overview article on INFRAFRONTIER as a European resource for studying the functional basis of human disease. The article highlights the platforms and resources that INFRAFRONTIER provides for ageing research, an more generally how INFRAFRONTIER promotes the global sharing of high-quality resources and data and thus contributes to data reproducibility and animal welfare.

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Obesity, Diabetes and Epigenetic Inheritance Study: ‘You are what your parents ate’

14 Apr 2016

Scientists at Helmholtz Zentrum München (HMGU), in collaboration with the  Technical University of Munich (TUM) and the German Center for Diabetes Research (DZD), have shown that diet-induced obesity and diabetes can be epigenetically inherited by the offspring via both the oocytes and the sperm.

The results were  published in Nature Genetics and have received broad international media attention.

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INFRAFRONTIER present at Transgenic Technology Meeting 2016

17 Mar 2016

INFRAFRONTIER will be present at the ISTT 13th Transgenic Technology Meeting, March 20-23, Prague, Czech Republic.  

You are welcome to visit us at stand 25 and learn more about INFRAFRONTIER!

Link to ISTT meeting

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INFRAFRONTIER is a Landmark on the new ESFRI Roadmap 2016

11 Mar 2016

The European Strategy Forum on Research Infrastructures (ESFRI) officially launched its Roadmap 2016 Report on an event held in Amsterdam on 10 March 2016 organised under the Dutch EU Presidency.

The Report lists 29 “ESFRI Landmarks”, one of them is INFRAFRONTIER. ESFRI Landmarks are research infrastructures that were implemented or started implementation before 2015 and are now considered “major elements of competitiveness of the European Research Area”.

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Detailed protocol of GEMM-ESC strategy published in Nature Protocols

12 Nov 2015

GEMM-ESC protocol published in EMBO Molecular Medicine last year, the Netherlands Cancer Institute (NKI) presented a strategy for rapid analysis of gene function in mouse models by deriving and modifying embryonic stem cells (ESC) from validated genetically engineered mouse models (GEMM), the so-called GEMM-ESC strategy.

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The INFRAFRONTIER GmbH is hiring

22 Oct 2015

The INFRAFRONTIER GmbH has opened postitions. If you are a highly-motivated person and want to leave your mark in a small and innovative team, please check our job advertisements.

Open positions

Geneticist for Scientific User Support m/f (part-time)

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H2020 projects CORBEL and RItrain start with INFRAFRONTIER participation

15 Sep 2015

INFRAFRONTIER is partner in two new Horizon 2020 projects that started on 01 September: CORBEL and RItrain.

CORBEL brings together the ESFRI Biological and Medical Research Infrastructures (BMS RI) to develop common services and harmonised access procedures to facilitate groundbreaking interdisciplinary research in the area of the life sciences. Together, the BMS RI cover the entire range from the discovery of basic biological mechanisms to applied medical translation.

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Blastocyst genotyping for quality control of mouse mutant archives: an ethical and economical approach.

26 Aug 2015

Mutant mouse strains generated and phenotyped by the International Mouse Phenotyping Consortium are made available to the research community via public repositories, mostly as cryopreserved sperm or embryos. To ensure the quality of this frozen resource there is a requirement that for each strain the frozen sperm/embryos are proven able to produce viable mutant progeny, before the live animal resource is removed from cages.

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Primary Phenotyping of Mouse Embryos: Phenomin Training Course

5 Aug 2015

A course on primary phenotyping of mouse embryos will take place at the Institute Clinique de la Souris, November 25-27, 2015.

The course is aimed at providing a theoretical and practical background knowledge destined for researchers and engineers that are willing to acquire primary expertise in mouse development. The topics will cover dissection of post implant embryos, histology, whole mount Lac Z staining and confocal imaging of whole embryos.

For further information please contact: Olivia Wendling, ICS

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IPAD-MD project kicked-off in Munich

29 Jul 2015

On July 21-22, INFRAFRONTIER IPAD-MD project was kicked-off, in a two-day meeting in Munich, Germany.

The Kick-Off meeting was aimed at:

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Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics

28 Jul 2015

The function of the majority of genes in the mouse and human genomes remains unknown. The mouse embryonic stem cell knockout resource provides a basis for the characterization of relationships between genes and phenotypes. The EUMODIC consortium developed and validated robust methodologies for the broad-based phenotyping of knockouts through a pipeline comprising 20 disease-oriented platforms. This consortium developped new statistical methods for pipeline design and data analysis aimed at detecting reproducible phenotypes with high power.

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EMMA partners offer 3 cryocourses in autum 2015

22 Jun 2015

EMMA partners offer a total of 3 cryocourses in autum 2015

 

  1. University of Veterinary Medicine Vienna, Cryo & Embryo Transfer Course, September 7-11, 2015
  2.  MRC Harwell Cryocourse, September 21-24, 2015
  3.  CNR Monterotondo, Workshop on Cryopreservation and Recovery Techniques in the Laboratory Mouse, November 16-20, 2015

 

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Reproducibility: Use mouse biobanks or lose them

20 Jun 2015

Reproducibility: Use mouse biobanks or lose them, Nature | Comment 10 June 2015 Kent Lloyd, Craig Franklin, Cat Lutz & Terry Magnuson Now that genetic engineering of mice is so easy, centralized repositories are essential, argue Kent Lloyd and colleagues.

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First INFRAFRONTIER project funded under EC Horizon 2020: IPAD-MD Grant Agreement signed

15 May 2015

The IPAD-MD project, Research Infrastructures for Phenotyping, Archiving and Distribution of Mouse Diseases Models, will address the coordination and cooperation between INFRAFRONTIER and complementary research infrastructures world-wide contributing to the global effort of IMPC, has been funded under the EC Horizon 2020 Programme.

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The INFRAFRONTIER GmbH has opened a position for a Senior Database and Web Developer

5 May 2015

The INFRAFRONTIER GmbH is hiring. If you are a highly-motivated person and want to leave your mark in a small and innovative team, please check our job advertisements.

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Next MRC Harwell cryo-course will be held in September 2015 - registration open

16 Mar 2015

The course is intended to give animal technologists hands-on experience of the murine embryo and spermatozoa freezing techniques routinely used at Harwell. In addition, delegates will gain experience of a simple and robust in vitro fertilization procedure.

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Workshop Mouse Microbiota: genotype-phenotype control and technological challenges

17 Feb 2015

The Workshop Mouse Microbiota  will take place on 26 - 27 March  2015 at the Instituto Gulbenkian de Ciência, Oeiras, Portugal.

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Training Course: Primary phenotyping of mouse embryos

29 Jan 2015

On 17-19 March 2015, a training course on primary phenotyping of mouse embryos will take place at Institute Clinique de la Souris, Illkirch, France.

The course is aimed at providing both theoretical and practical background knowledge targeted at researchers and engineers, willing to acquire primary expertise in mouse development.
The topics will cover dissection of post implant embryos, histology, whole mount Lac Z staining and confocal imaging of whole embryos.

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INFRAFRONTIER supports the campaign for a European Year for Rare Diseases in 2019

19 Jan 2015

EURORDIS, the alliance of European patient organisations for rare diseases, campains for a European Year on Rare Diseases 2019. This should raise awareness for the 30 million Europeans who suffer from a rare disease and encourage research that focuses on these rare, mostly unknown, seriously debilitating and often life-threatening diseases.

INFRAFRONTIER, provider of resources and services for rare diseases research, strongly supports the EURORDIS campaign.

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3rd Council Meeting of the INFRAFRONTIER GmbH took place in Munich

20 Dec 2014

On 19 November 2014 the Council of the INFRAFRONTIER GmbH met in Munich for its third regular meeting. The Council discussed and approved the work programme, budget and the overall scientific strategy for the INFRAFRONTIER GmbH in 2015.

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INFRAFRONTIER resources and web portal will be published in Nucleic Acids Research Database Issue

16 Dec 2014

A publication describing the INFRAFRONTIER service portfolio and the web portal that gives access to all of them has been accepted for the next Database Issue of Nucleic Acids Research. Advance access is available on the NAR webpage.

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German Mouse Clinic certified under the International Standard ISO 9001:2008

24 Nov 2014

The management system of German Mouse Clinic has been successfully audited and certified by TÜV SÜD according to the Quality Management System Standards EN ISO 9001: 2008.

Reproducibility and traceability of analytical data, documentation, transparency and continuity are the cornerstones of the German Mouse Clinic quality management system. The certification reflects the German Mouse Clinic commitment to promote research activities at the highest level in science and scientific standards.

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The INFRAFRONTIER GmbH has open positions for a Web Developer and a Head of Unit - INFRAFRONTIER Mouse Clinics

14 Nov 2014

The INFRAFRONTIER GmbH is hiring. If you are a highly-motivated person and want to leave your mark in a small and innovative team, please check our job advertisements.

Open positions

Web developer m/f

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Cryoport and EMMA enter into global agreement to provide full-service logistics solutions for frozen biomaterials

14 Aug 2014

Cryoport, Inc. the only end-to-end cryogenic logistics solutions provider, entered into an agreement with the European Mouse Mutant Archive (EMMA), a part of INFRAFRONTIER, the European Research Infrastructure for phenotyping and archiving of model mammalian genomes

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genOway offers industry scientists immediate access to EUCOMM conditional KO mouse models

2 Jul 2014

genOway guarantees freedom to operate (FTO) and offers important time gain in conditional knockout development time for industry scientists.

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Monterotondo laboratory course on cryopreservation of mouse germplasm

1 Jul 2014

From 20 to 24 October 2014 the CNR Monterotondo and The Jackson Laboratory offer a comprehensive course on cryopreservation of mouse embryos, sperm and ovaries. The course is financially supported by the EC FP7 Capacities Specific Program through the INFRAFRONTIER-I3 project.

 

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Council Meeting of the INFRAFRONTIER GmbH held in Munich

13 May 2014

On 07 May 2014 the Council of the INFRAFRONTIER GmbH met in Munich. This was the first meeting of the Council after the accession of France, Czech Republic, Finland and Greece to the INFRAFRONTIER GmbH on 05 December 2013.

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INFRAFRONTIER IMPC Workshop: Promoting the international exchange of mouse mutant resources, Munich, Germany

12 May 2014

The INFRAFRONTIER  IMPC workshop: Promoting the international exchange of mouse mutant resources, took place in Munich, Germany, 08-09 May 2014.

The main objectives of the workshop were to discuss how to simplify the international exchange of mouse mutant resources and to define the procedural changes to achieve it, to review the key issues facing the mouse community and mouse repositories as well as focus on IP issues and to present best practices in sharing research tools

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INFRAFRONTIER IMPC Phenotyping Workshop, San Francisco, USA

21 Mar 2014

The INFRAFRONTIER IMPC Phenotyping Workshop took place in San Francisco, California, USA, 19 - 20 March 2014, attracting the participation of around 60 international delegates.

The main aims of the Phenotyping Workshop were to assess tests, progress and phenotype detection, as well as to discuss the test implementation for IMPC Phase II.

The Phenotyping Workshop was funded through the INFRAFRONTIER InfraCoMP Project.

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Free of charge mouse phenotyping service for European researchers

27 Feb 2014

Second phenotyping call of the EC FP7 funded INFRAFRONTIER-I3 project open until March 15, 2014.

A total of 22 mouse mutant lines can be characterised through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease.

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Next MRC Harwell cryo-course will be held in March 2014 - registration open

20 Dec 2013

The course is intended to give animal technologists hands-on experience of the murine embryo and spermatozoa freezing techniques routinely used at Harwell. In addition, delegates will gain experience of a simple and robust in vitro fertilization procedure.

 

Participants will gain first-hand experience in following techniques:

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France, Greece, Czech Republic and Finland enter the INFRAFRONTIER GmbH

5 Dec 2013

France, Greece, Czech Republic and Finland enter the INFRAFRONTIER GmbH

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INFRAFRONTIER IMPC IKMC Rome Meeting with more than 200 participants on Dec 02-04

29 Nov 2013

On 02 to 04 December, INFRAFRONTIER holds an international workshop in Rome, together with the International Mouse Phenotyping Consortium (IMPC) and the International Knockout Mouse Konsortium (IKMC). More than 200 participants will participate.

The aim of the Rome meeting is to discuss how researchers from different scientific fields and from industry can benefit from the large-scale mouse genomics initiatives INFRAFRONTIER, the IMPC and the IKMC, and to obtain feedback from the research community on future needs and improvements.

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Universitat Autònoma de Barcelona training course on mouse osteology

20 Nov 2013

The aim of this INFRAFRONTIER training course held from 20 to 22 Novembeer 2013 at the Universitat Autònoma de Barcelona (UAB), Spain is capacitating participants to localize and to interpret the most common skeletal morphological abnormalities found in mutant mice. This will occur in the context of dedicated learning sessions devoted to the study of bone anatomy and the methodologies (X-ray, CT, Alizarin staining, etc) used to visualize the mouse skeleton. Each lecture will be followed by a practical session in which participants will work with real bone specimens and CT images.

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Monterotondo laboratory course on cryopreservation of mouse germplasm (2013)

21 Oct 2013

From 21 to 25 October 2013 the CNR Monterotondo and The Jackson Laboratory offer a comprehensive course on cryopreservation of mouse embryos, sperm and ovaries. The course is financially supported by the EC FP7 Capacities Specific Program through the INFRAFRONTIER-I3 project.

 

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First INFRAFRONTIER-I3 project Transnational Access call for mouse production published

7 Mar 2013

FP7 funded INFRAFRONTIER-I3 project (2013-2016) supports eligible customers with a free of charge mouse production service implemented as a Transnational Access (TA) activity providing a total of 30 access units. The access unit is defined by the production of a minimum of two heterozygous mice carrying the targeted gene allele of choice from the corresponding validated gene-targeted ES cell clone(s).

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INFRAFRONTIER highlighted in the 2013 ESFRI brochure on 'European Research Infrastructures with global impact'

4 Mar 2013

INFRAFRONTIER project was included in a selection of ESFRI projects, currently in implementation phase, to feature in the ESFRI brochure on 'European Research Infrastructures with global impact', published for the 10th anniversary of ESFRI. With the publication of this brochure, ESFRI intents to make the general public more broadly aware of the ESFRI itself and of the goals of the different ESFRI Research Infrastructures.

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