Mice produced from the IKMC resource are among the most frequently ordered mutant mouse lines from the EMMA repository. Detailed information on the IKMC resource is provided on the website of the International Mouse Phenotyping Consortium.
The groups funded to produce IKMC knockout alleles use targeting constructs that have different and complementary properties. A general outline of these constructs that may be helpful in the assessment of the preferred approach for targeting the gene(s) of interest is described at http://www.knockoutmouse.org/about/targeting-strategies.
A comprehensive overview of FAQs related to the IKMC resource e.g. related to quality controls and genotyping and downloads such as an allele conversion guide are available at the IKMC knowledgebase.