The phenotyping protocols that are used by mouse clinics participating in the Transnational Activity of the INFRAFRONTIER-I3 project are part of the IMPC core pipeline and contained in the IMPReSS database. IMPReSS (International Mouse Phenotyping Resource of Standardised Screens) contains standardized phenotyping protocols which are essential for the characterization of mouse phenotypes. IMPReSS contains definitions of the phenotyping pipelines and mandatory and optional procedures and parameters carried out and data collected by international mouse clinics following the protocols defined. This allows data to be comparable and shareable and ontological annotations permit interspecies comparison which may help in the identification of phenotypic mouse-models of human diseases.
The IMPC Adult and Embryonic Phenotype Pipeline
The IMPC (International Mouse Phenotyping Consortium) core pipeline describes the phenotype pipeline that has been agreed by the participating research institutions. The pipeline is currently in development. The protocols in the core IMPC Pipeline are being developed by the IMPC phenotyping working groups and the current versions on this site are still under final review. The phenotyping working groups are working closely with the data wranglers to complete an agreed first version. Updates on the progress of this will be available through IMPReSS.