ISIDORe Open Calls

The ISIDORe – “Integrated Services for Infectious Disease Outbreak Research” project was officially launched on 24th February 2022 under the Horizon Europe Framework Programme in response to the call on Research infrastructure services for rapid research responses to COVID-19 and other infectious disease epidemics (HORIZON-INFRA-2021-EMERGENCY-02). The 21M€ EU-funded large-scale project assembles an unprecedented One Health-driven, integrated portfolio of cutting-edge research services and resources, ranging from fundamental to applied, dedicated to the study of epidemic-prone diseases including SARS-CoV-2 variants.

Under this project, INFRAFRONTIER offers a host of cutting-edge free-of-charge services to support research projects on SARS-CoV-2, its variants and other potential pathogens.

COVID-19 BSL3 Pipeline

This ISIDORe Open Call provides extensive user support to the selected projects for assessing novel potential vaccine and treatment compounds for COVID-19 in preclinical mouse models. Click here to know more and apply.


Multi-site Immuno analysis

Based on the principle of metal tag detection by mass cytometry, this technique allows in-house analysis of samples from distant BSL3 labs hosting specific infectious models of interest.



Humanisation of mouse models

This service offers expression of hACE2 in user provided mouse cohorts. AAV particles are used as vectors for transient expression of human ACE2 in upper and/or lower respiratory tract and lungs. The humanization can be directed to upper respiratory tract by nasal application of AAV particles and to lower respiratory tract by forced tracheal inhalation.