- abnormal coat/ hair morphology / MGI
- alopecia / MGI
- sparse hair / MGI
- delayed hair appearance / MGI
- enlarged sebaceous gland / MGI
- enlarged lymph nodes / MGI
- dermatitis / MGI
- skin lesions / MGI
- epidermal hyperplasia / MGI
- thick dermal layer / MGI
- decreased body size / MGI
- corneal opacity / MGI
- excessive scratching / MGI
- acanthosis / MGI
- abnormal hair growth / MGI
- abnormal hair follicle development / MGI
- abnormal hair shaft morphology / MGI
- abnormal external auditory canal morphology / MGI
- abnormal hair cycle catagen phase / MGI
- orthokeratosis / MGI
- integument phenotype / MGI
- dental pulp necrosis / MGI
- periodontal ligament necrosis / MGI
- abnormal leukocyte cell number / MGI
- abnormal thymus morphology / MGI
- thick epidermis / MGI
- abnormal lymph node morphology / MGI
- abnormal lymph node cortex morphology / MGI
- abnormal thymus lobule morphology / MGI
- abnormal immune system organ morphology / MGI
- decreased CD4-positive, alpha beta T cell number / MGI
- increased CD8-positive, alpha-beta T cell number / MGI
- abnormal thymus corticomedullary boundary morphology / MGI
- dilated lymph node medullary sinus / MGI
- enlarged thymus cortex / MGI
- abnormal hair follicle morphology / MGI
- postnatal growth retardation / MGI
- increased inflammatory response / MGI
- liver inflammation / MGI
- thymus atrophy / MGI
- lymph node inflammation / MGI
- cachexia / MGI
- lymph node hyperplasia / MGI
- hypergranulosis / MGI
- rough coat / MGI
- postnatal lethality, incomplete penetrance / MGI
STOCK Ctslnkt/Ieg
Status | Available to order |
EMMA ID | EM:00136 |
International strain name | STOCK Ctslnkt/Ieg |
Alternative name | nkt, nackt |
Strain type | Induced Mutant Strains : Radiation-induced |
Allele/Transgene symbol | Ctslnkt, |
Gene/Transgene symbol | Ctsl |
Information from provider
Provider | Dietmar Schlote |
Provider affiliation | Martin-Luther University, Halle/Wittenberg |
Phenotypic information | hair loss, CD4 deficiency |
References |
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Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
MGI phenotypes (allele matching)
Literature references
- Nackt (nkt), a new hair loss mutation of the mouse with associated CD4 deficiency.;Benavides F, Giordano M, Fiette L, Bueno Brunialti A L, Martin Palenzuela N, Vanzulli S, Baldi P, Schmidt R, Dosne Pasqualini C, Guénet J, ;1999;Immunogenetics;49;413-9; 10199917
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