- mammalian phenotype / IMPC
- decreased bone mineral density / IMPC
- abnormal body length / IMPC
- decreased body weight / IMPC
- abnormal cornea morphology / IMPC
- hyperactivity / IMPC
- increased startle reflex / IMPC
- abnormal bone mineralization / IMPC
- abnormal bone structure / IMPC
- increased lean body mass / IMPC
- decreased lean body mass / IMPC
- abnormal behavior / IMPC
- decreased prepulse inhibition / IMPC
- increased total body fat amount / IMPC
- decreased grip strength / IMPC
STOCK Ostes/H
Status | Available to order |
EMMA ID | EM:00187 |
International strain name | STOCK Ostes/H |
Alternative name | Ost |
Strain type | Induced Mutant Strains : Chemically-induced |
Allele/Transgene symbol | Ostes, |
Gene/Transgene symbol | Ostes |
Information from provider
Provider | Gonzalo Blanco |
Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
Phenotypic information | Mice carrying this mutation are small in size, exhibit muscle wasting and muscular dystrophy. Mice homozygous for this mutation show tremors when suspended by the tail. |
References |
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Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
IMPC phenotypes (allele matching)
Literature references
- A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.;Nolan P M, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray I C, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel K P, Voegeling S, Guenet J L, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher E M, Martin J, Rastan S, Brown S D, Hunter J, ;2000;Nature genetics;25;440-3; 10932191
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