STOCK Ostes/H

Status

Available to order

EMMA IDEM:00187
International strain nameSTOCK Ostes/H
Alternative nameOst
Strain typeInduced Mutant Strains : Chemically-induced
Allele/Transgene symbolOstes,
Gene/Transgene symbolOstes

Information from provider

ProviderGonzalo Blanco
Provider affiliationMammalian Genetics Unit, Mary Lyon Centre at MRC Harwell
Phenotypic informationMice carrying this mutation are small in size, exhibit muscle wasting and muscular dystrophy. Mice homozygous for this mutation show tremors when suspended by the tail.
References
  • A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.;Nolan P M, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray I C, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel K P, Voegeling S, Guenet J L, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher E M, Martin J, Rastan S, Brown S D, Hunter J, ;2000;Nature genetics;25;440-3; 10932191

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (allele matching)
  • mammalian phenotype / IMPC
  • decreased bone mineral density / IMPC
  • abnormal body length / IMPC
  • decreased body weight / IMPC
  • abnormal cornea morphology / IMPC
  • hyperactivity / IMPC
  • increased startle reflex / IMPC
  • abnormal bone mineralization / IMPC
  • abnormal bone structure / IMPC
  • increased lean body mass / IMPC
  • decreased lean body mass / IMPC
  • abnormal behavior / IMPC
  • decreased prepulse inhibition / IMPC
  • increased total body fat amount / IMPC
  • decreased grip strength / IMPC
MGI phenotypes (allele matching)
  • tremors / MGI
  • dystrophic muscle / MGI
  • abnormal motor capabilities/coordination/movement / MGI
  • muscular atrophy / MGI

Literature references

  • A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.;Nolan P M, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray I C, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel K P, Voegeling S, Guenet J L, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher E M, Martin J, Rastan S, Brown S D, Hunter J, ;2000;Nature genetics;25;440-3; 10932191

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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