STOCK Gt(ROSA)26Sortm2(cre/ERT2)Brn/Cnrm
| Status | Available to order |
| EMMA ID | EM:00410 |
| International strain name | STOCK Gt(ROSA)26Sortm2(cre/ERT2)Brn/Cnrm |
| Alternative name | RCM2 |
| Strain type | Targeted Mutant Strains : Knock-in |
| Allele/Transgene symbol | Gt(ROSA)26Sortm2(cre/ERT2)Brn, |
| Gene/Transgene symbol | Gt(ROSA)26Sor |
Information from provider
| Provider | Anton Berns |
| Provider affiliation | Research - Animal Facility, The Netherlands Cancer Institute |
| Genetic information | Knock-in of cre recombinase/ERT2, pgk-puromycin resistance cassette in the Gt(ROSA)26Sor gene. Similar to Vooijs et al. EMBO Rep, 2001 (4) 292-297. |
| Phenotypic information | RCM2 mice show no obvious phenotype. |
| Breeding history | Mutation was introduced in a 129 ES line, backcrossed to C57BL/6 background. The RCM2 strain is now being backcrossed to FVB/N. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues.;Hameyer Dorothe, Loonstra Ate, Eshkind Leonid, Schmitt Steffen, Antunes Cecilia, Groen Annemiek, Bindels Eric, Jonkers Jos, Krimpenfort Paul, Meuwissen Ralph, Rijswijk Loes, Bex Axel, Berns Anton, Bockamp Ernesto, ;2007;Physiological genomics;31;32-41; 17456738