MGI phenotypes (allele matching)
C3H;C-Ta33Hl/H
| Status | Available to order |
| EMMA ID | EM:01170 |
| International strain name | C3H;C-Ta33Hl/H |
| Alternative name | INH/6 |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Ta33Hl, |
| Gene/Transgene symbol | Ta33Hl |
Information from provider
| Provider | Neil Dear |
| Provider affiliation | MRC Mammalian Genetics Unit |
| Genetic information | The Tabby mutation (anhidrotic ectodermal dysplasia) is a mouse model for X-linked hypohirotic ectodermal dysplasia. This is a congenital disorder resulting in abnormal tooth, hair and sweat gland development. Note: this may not be the case in this particular Tabby mutation as the teeth superficially appear to be normal. |
| Phenotypic information | Heterozygous females are striped. Hemizygous males have no guard hairs, hair on tails, normal teeth, very little hair behind the ears. Homozygous females look like hemizygous males. |
| Breeding history | Original background: C3H/HeH x BALB/c. Maintained background: C3H/HeH backcross. Breeding History: Backcrossed to C3H/HeH for several generations. |
| References |
|
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Literature references
- A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.;Nolan P M, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray I C, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson J A, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel K P, Voegeling S, Guenet J L, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher E M, Martin J, Rastan S, Brown S D, Hunter J, ;2000;Nature genetics;25;440-3; 10932191