STOCK Lim2To3/H
Status | Available to order |
EMMA ID | EM:01706 |
International strain name | STOCK Lim2To3/H |
Alternative name | To3 |
Strain type | Induced Mutant Strains : Chemically-induced |
Allele/Transgene symbol | Lim2To3, |
Gene/Transgene symbol | Lim2 |
Information from provider
Provider | Mary Lyon |
Provider affiliation | MRC Mammalian Genetics Unit |
Phenotypic information | Total lens opacity with microphthalmia in homozygotes. |
References |
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Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI allele-associated human disease models
Orphanet associated rare diseases, based on orthologous gene matching
- Total early-onset cataract / Orphanet_98994
MGI phenotypes (allele matching)
Literature references
- Identification of a mutation in the MP19 gene, Lim2, in the cataractous mouse mutant To3.;Steele E C, Kerscher S, Lyon M F, Glenister P H, Favor J, Wang J, Church R L, ;1997;Molecular vision;3;5; 9238094
- Two new cataract loci, Ccw and To3, and further mapping of the Npp and Opj cataracts in the mouse.;Kerscher S, Glenister P H, Favor J, Lyon M F, ;1996;Genomics;36;17-21; 8812411
- A comparison of the dominant cataract and recessive specific-locus mutation rates induced by treatment of male mice with ethylnitrosourea.;Favor J, ;1983;Mutation research;110;367-82; 6877261
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