C57BL/6J-Tg(Vpreb1-IL2RB)F133Ilm/H
Status | Available to order |
EMMA ID | EM:01895 |
International strain name | C57BL/6J-Tg(Vpreb1-IL2RB)F133Ilm/H |
Alternative name | Tg(-214VpreB1-huCD122)F133Lmb |
Strain type | Transgenic Strains |
Allele/Transgene symbol | Tg(Vpreb1-IL2RB)F133Ilm, |
Gene/Transgene symbol | Tg(Vpreb1-IL2RB)F133Ilm |
Information from provider
Provider | Dr Lill Martensson |
Provider affiliation | The Babraham Institute, Babraham, Cambridge, CB2 4PB |
Genetic information | The human interleukin 2 receptor, beta (IL2RB or CD122) is expressed on the cell surface of precursor B-lymphocytes (stage specific) and as mRNA in some other tissues. |
Phenotypic information | The Vpreb1 promoter/enhancer-driven reporter gene (human IL2RB or CD122) gives rise to B-lymphocyte stage-specific expression. However, it is also expressed in other tissues. Expression is copy number-dependent. |
References |
|
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- The VpreB1 enhancer drives developmental stage-specific gene expression in vivo.;Licence Steve, Persson Christine, Mundt Cornelia, Mårtensson Inga-Lill, ;2003;European journal of immunology;33;1117-26; 12672078
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).