MGI phenotypes (allele matching)
STOCK Mut921/H
| Status | Available to order |
| EMMA ID | EM:01952 |
| International strain name | STOCK Mut921/H |
| Alternative name | MUT/921 |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Mut921, |
| Gene/Transgene symbol | Mut921 |
Information from provider
| Provider | Bruce Cattanach |
| Provider affiliation | MRC Harwell, Didcot, Oxon, OX11 0RD |
| Genetic information | Dominant. Recovered following spermatogonial exposure to a combined chemical (triethylenemelamine (TEM) + 3-aminobenzamide) + 6 Gy X-ray treatment to a (C3H/HeH x 101/H)F1 male mated to tester stock (PT) female. |
| Phenotypic information | Key feature of heterozygotes is a short broad head, wide between eyes, shortened nasal passage with occasional indication of cleft. White feet and belly spots also seen. Small at birth and weaning (approx 30% lighter than wild-type sibs). Recovery at birth reduced due to some prenatal loss of foetuses with more extreme head abnormality. Viability from birth to weaning is circa 60%. Homozygotes are probably lethal pre-implantation. |
| Breeding history | Original background: (C3H/HeH x 101/H) x PT. Maintained background: C3H/HeH x 101/H. Breeding History: Backcrossed to C3H/HeH x 101/H for several generations. |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |