STOCK Smg6Tg(SMN1*delta5)1Pks/H

Status

Available to order

EMMA IDEM:02416
International strain nameSTOCK Smg6Tg(SMN1*delta5)1Pks/H
Alternative nameSMNDelta5
Strain typeTransgenic Strains
Allele/Transgene symbolSmg6Tg(SMN1*delta5)1Pks,
Gene/Transgene symbolSmg6

Information from provider

ProviderNicholas Parkinson
Provider affiliationUniversity of Oxford
Genetic informationThis line overexpresses a cDNA splice isoform of human SMN that is missing exon 5, SMNDelta5. The promoter is a 750bp fragment of the human SMN1 promoter. The transgene is stably integrated as a single copy into Intron 13 of the Smg6 locus on Chromosome 11. This transgene is maintained as a heterozygote on an FVB/N background and expresses in all tissues tested. Heterozygotes have no deleterious phenotype on a wildtype background but homozygotes are embryonic lethal.
Phenotypic informationNone
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom
Animals used for archivingheterozygous FVB/N
Breeding at archiving centreMales were archived by sperm freezing on arrival. No breeding was performed at the archiving centre.

Disease and phenotype information

MGI phenotypes (allele matching)
  • embryonic lethality / MGI

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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