STOCK Smad2tm5(SMAD2)Rob/H

Status

Available to order

EMMA IDEM:02512
International strain nameSTOCK Smad2tm5(SMAD2)Rob/H
Alternative nameSmad2 FL
Strain typeTargeted Mutant Strains : Knock-in
Allele/Transgene symbolSmad2tm5(SMAD2)Rob,
Gene/Transgene symbolSmad2

Information from provider

ProviderElizabeth Robertson
Provider affiliationSir William Dunn School of Pathology, University of Oxford
Genetic informationKnock-in allele of Smad2 of a FLAG tagged human cDNA sequence into exon1 of the Smad2 gene. Resulting allele expresses full length human Smad2 in place of endogenous Smad2.
Phenotypic informationEmbryonic lethal at 8.5 dpc.
Breeding historyBackcrossed to 129/SvEv.
References
  • Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile.;Dunn N Ray, Koonce Chad H, Anderson Dorian C, Islam Ayesha, Bikoff Elizabeth K, Robertson Elizabeth J, ;2005;Genes & development;19;152-63; 15630024
Homozygous fertileno
Homozygous viableno
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

Literature references

  • Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile.;Dunn N Ray, Koonce Chad H, Anderson Dorian C, Islam Ayesha, Bikoff Elizabeth K, Robertson Elizabeth J, ;2005;Genes & development;19;152-63; 15630024

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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