STOCK Smad9tm2Rob/H
| Status | Available to order |
| EMMA ID | EM:02524 |
| International strain name | STOCK Smad9tm2Rob/H |
| Alternative name | Smad8 Conditional |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Smad9tm2Rob, |
| Gene/Transgene symbol | Smad9 |
Information from provider
| Provider | Elizabeth Robertson |
| Provider affiliation | Sir William Dunn School of Pathology, University of Oxford |
| Genetic information | Knock in of loxP flanked exon 2-3 locus at the Smad8 locus enables conditional inactivation of Smad8 in vivo via Cre mediated recombination and excision of Smad8 coding sequences. |
| Phenotypic information | No overt phenotype. |
| Breeding history | Outcrossed to CD1. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo.;Arnold Sebastian J, Maretto Silvia, Islam Ayesha, Bikoff Elizabeth K, Robertson Elizabeth J, ;2006;Developmental biology;296;104-18; 16765933