- mammalian phenotype / IMPC
- decreased bone mineral density / IMPC
- decreased body weight / IMPC
- macrophthalmia / IMPC
- hypoactivity / IMPC
- increased circulating phosphate level / IMPC
- abnormal glucose homeostasis / IMPC
- abnormal bone mineralization / IMPC
- increased lean body mass / IMPC
- decreased lean body mass / IMPC
- abnormal behavior / IMPC
- increased total body fat amount / IMPC
C57BL/6NTac-Cisd2tm1a(EUCOMM)Wtsi/H
Status | Available to order |
EMMA ID | EM:04395 |
International strain name | C57BL/6NTac-Cisd2tm1a(EUCOMM)Wtsi/H |
Alternative name | EPD0143_2_C03 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Cisd2tm1a(EUCOMM)Wtsi, |
Gene/Transgene symbol | Cisd2 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | MRC, Medical Research Council |
Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
Genetic information | This mouse line originates from EUCOMM ES clone EPD0143_2_C03. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Animals used for archiving | heterozygous C57BL/6NTac |
Breeding at archiving centre | Chimeras were mated to C57BL/6NTac (USA) and maintained on this background thereafter. |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Wolfram syndrome / Orphanet_3463
IMPC phenotypes (allele matching)
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