STOCK Scnn1gtm1.1Hum/Orl

Status

Available to order

EMMA IDEM:04400
International strain nameSTOCK Scnn1gtm1.1Hum/Orl
Alternative nameScnn1g lox/lox
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolScnn1gtm1.1Hum,
Gene/Transgene symbolScnn1g

Information from provider

ProviderEdith Hummler
Provider affiliationPharmacology & Toxicology, University of Lausanne
Genetic informationAn frt-flanked neo cassette with a 3' loxP site was inserted upstream of exon 2, and an additional loxP site was inserted downstream of exon 2. Germ line, flp-recombination was used to remove the neo cassette.
Phenotypic informationNo phenotype.
References
  • Conditional gene targeting of the ENaC subunit genes Scnn1b and Scnn1g.;Mérillat Anne-Marie, Charles Roch-Philippe, Porret Andrée, Maillard Marc, Rossier Bernard, Beermann Friedrich, Hummler Edith, ;2009;American journal of physiology. Renal physiology;296;F249-56; 19036848
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreInstitut de Transgenose, INTRAGENE, Orléans, France
Animals used for archivinghomozygous , wild-type C57BL/6N

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

Literature references

  • Conditional gene targeting of the ENaC subunit genes Scnn1b and Scnn1g.;Mérillat Anne-Marie, Charles Roch-Philippe, Porret Andrée, Maillard Marc, Rossier Bernard, Beermann Friedrich, Hummler Edith, ;2009;American journal of physiology. Renal physiology;296;F249-56; 19036848

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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