STOCK Fcamrtm1.2Jsv/Cnbc
| Status | Available to order |
| EMMA ID | EM:04667 |
| International strain name | STOCK Fcamrtm1.2Jsv/Cnbc |
| Alternative name | FcamR (4D6)- Null |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Fcamrtm1.2Jsv, |
| Gene/Transgene symbol | Fcamr |
Information from provider
| Provider | Sjef Verbeek |
| Provider affiliation | Human Genetics, Leiden University Medical Center (LUMC) |
| Genetic information | Anti-sense insertion in intron 3 of Neo selection marker flanked by Frt sites and 5' loxP. In addition, insertion of one loxP site in intron 4. By breeding to the EIIaCre deleter mouse line, the Neo selection marker and intron 4 were deleted to obtain the "FcamR-null" mouse. |
| Phenotypic information | In the kidney, a 50% expression of the RNA coding for a soluble receptor is detected. |
| Breeding history | Chimera crossed to EIIaCre deleter mouse. F1 crossed to C57BL/6. F2 intercrossed. Homozygous (cre recombinase negative) animals selected for further breeding. |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | homozygous C57BL/6J, wild-type C57BL/6J |
| Stage of embryos | 8-cell |