| Status | Available to order |
| EMMA ID | EM:04764 |
| International strain name | STOCK Tyrc-m/Cnbc |
| Alternative name | Tyr |
| Strain type | Spontaneous |
| Allele/Transgene symbol | Tyrc, |
| Gene/Transgene symbol | Tyr |
| Provider | Lluis Montoliu |
| Provider affiliation | Departamento de Biologia Molecular y Celular, CNB-CSIC, Centro Nacional de Biotecnologia |
| Additional owner | The original Tyr |
| Genetic information | Mice carrying the Tyrc-m "chinchilla mottled" allele were imported as live animals from MRC Harwell (FESA), Peter Glenister, in 2001 after rescuing the line from frozen embryos. Genotype received included: Tyrc-m/Tyrc-m, a/a, +/Ednrbs. Since then they were bred to albino outbred Hsd:NMRI mice and eventually maintained as homozygous Tyrc-m/Tyrc-m. |
| Phenotypic information | Tyrc-m "chinchilla mottled" mice have dark and light mottled coat, usually seen as "stripes or patches". Homozygous are darker (more pigmented) than heterozygous, which appear to be light grey. |
| Breeding history | Since 2001, the Tyrc-m chinchilla mottled allele it has been bred and maintained, as homozygous, in albino outbred Hsd:NMRI mouse strain. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | homozygous NMRI, wild-type NMRI |
| Stage of embryos | 8-cell |
Orphanet associated rare diseases, based on orthologous gene matching
