- belly spot / MGI
- impaired hearing / MGI
- increased or absent threshold for auditory brainstem response / MGI
- abnormal inner ear morphology / MGI
- absent semicircular canals / MGI
- short tail / MGI
- hyperactivity / MGI
- impaired righting response / MGI
- abnormal placing response / MGI
- deafness / MGI
- absent otoliths / MGI
- abnormal cochlear inner hair cell morphology / MGI
- abnormal vestibular labyrinth morphology / MGI
- head tossing / MGI
- dilated endolymphatic duct / MGI
- dilated endolymphatic sac / MGI
- abnormal otic vesicle development / MGI
- abnormal vestibular saccule morphology / MGI
- abnormal utricle morphology / MGI
- absent pinna reflex / MGI
- short scala media / MGI
STOCK Lmx1amtl/Cnbc
Status | Available to order |
EMMA ID | EM:04898 |
International strain name | STOCK Lmx1amtl/Cnbc |
Alternative name | Mutanlallemande |
Strain type | Spontaneous |
Allele/Transgene symbol | Lmx1amtl, |
Gene/Transgene symbol | Lmx1a |
Information from provider
Provider | Karen Steel |
Provider affiliation | Wellcome Trust Sanger Institute |
Additional owner | Yvan Lallemand and Jean-Louis Guenet, Institut Pasteur, discovered the mutant. |
Genetic information | A spontaneous mutation of Lmx1a. |
Phenotypic information | Homozygotes show severe head bobbing and circling, white belly spot or belt and are small. |
Breeding history | The mutant was introduced on a mixed genetic background and has been maintained within a closed colony for over ten years. |
References | None available |
Homozygous fertile | no |
Homozygous viable | yes |
Homozygous matings required | no |
Immunocompromised | not known |
Information from EMMA
Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
Disease and phenotype information
MGI phenotypes (allele matching)
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