C57BL/6N-Tlr9tm1.2Arte/Ieg
| Status | Available to order |
| EMMA ID | EM:05496 |
| International strain name | C57BL/6N-Tlr9tm1.2Arte/Ieg |
| Alternative name | Tlr9 KO conv |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Tlr9tm1.2 |
| Gene/Transgene symbol | Tlr9 |
Information from provider
| Provider | Helmholtz Zentrum Muenchen |
| Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen German Research Center for Environmental Health (GmbH) |
| Genetic information | Exon 2 has been flanked by loxP sites, as its genetic ablation should result in loss of function by deletion of most of the open reading frame (see EMMA strain EM:05497). The constitutive knock-out mutation has been obtained by in vivo cre recombinase-mediated deletion. |
| Phenotypic information | TO BE PROVIDED |
| Breeding history | Targeting performed in C57BL/6N ES cells and confirmed by Southern blotting. Tlr9 floxed mice were crossed to C57BL/6N cre-deleter mice to obtain the Tlr9 null allele. Maintained on C57BL/6N background. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C57BL/6NTac, wild-type C57BL/6N |
| Stage of embryos | 2-cell |