STOCK Otx2tm16Asim/2Cnrm
| Status | Available to order |
| EMMA ID | EM:05644 |
| International strain name | STOCK Otx2tm16Asim/2Cnrm |
| Alternative name | Otx2-Δm13 |
| Strain type | Targeted Mutant Strains : Other targeted |
| Allele/Transgene symbol | Otx2tm16Asim, |
| Gene/Transgene symbol | Otx2 |
Information from provider
| Provider | Antonio Simeone |
| Provider affiliation | Ceinge Biotecnologie Avanzate |
| Genetic information | Deletion of aminoacid 208 to 241 of Otx2 protein. |
| Phenotypic information | No phenotype. But when crossed with heterozygous Otx2 null mice, Otx2-/delta-m13 embryos showed severe head abnormalities. |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Combined pituitary hormone deficiencies, genetic forms / Orphanet_95494
- Butterfly-shaped pigment dystrophy / Orphanet_99001
- Colobomatous microphthalmia / Orphanet_98938
- Nanophthalmos / Orphanet_35612
- Syndromic microphthalmia type 5 / Orphanet_178364
- Septo-optic dysplasia spectrum / Orphanet_3157