STOCK Dp(16App-Runx1)5Yah/Orl
| Status | Available to order |
| EMMA ID | EM:05778 |
| International strain name | STOCK Dp(16App-Runx1)5Yah/Orl |
| Alternative name | Dp(16App-Runx1)5Yah |
| Strain type | Targeted Mutant Strains : Other targeted |
| Allele/Transgene symbol | Dp(16App-Runx1)5Yah, |
| Gene/Transgene symbol | Dp(16App-Runx1)5Yah |
Information from provider
| Provider | Yann HERAULT |
| Provider affiliation | TAAM-CDTA UPS44, Institut de Transgenose, INTRAGENE |
| Genetic information | This strain carries a duplication between App and Runx1 genes (MMU16). |
| Phenotypic information | No phenotype to date. |
| Breeding history | Male carrying a loxP site in Runx1 was mated to Hptr-Cre female. Female progeny carrying the loxP site in Runx1 and Hprt-Cre transgene was mated with a male carrying a loxP site in App gene. Female progeny carrying the 3 modifications was mated to C57BL/6 males to obtain the duplication. |
| References |
|
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6J, wild-type C57BL/6J |
Literature references
- Developmentally regulated promoter-switch transcriptionally controls Runx1 function during embryonic hematopoiesis.;Pozner Amir, Lotem Joseph, Xiao Cuiying, Goldenberg Dalia, Brenner Ori, Negreanu Varda, Levanon Ditsa, Groner Yoram, ;2007;BMC developmental biology;7;84; 17626615
- A Cre/loxP-deleter transgenic line in mouse strain 129S1/SvImJ.;Tang Shih-Huey E, Silva Francisco J, Tsark Walter M K, Mann Jeffrey R, ;2002;Genesis (New York, N.Y. : 2000);32;199-202; 11892008