STOCK Setd7tm1.1Ital/Flmg

Status

Available to order

EMMA IDEM:09467
International strain nameSTOCK Setd7tm1.1Ital/Flmg
Alternative nameB6.CBA-Setd7/Flmg
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolSetd7tm1.1Ital,
Gene/Transgene symbolSetd7

Information from provider

ProviderIannis Talianidis
Provider affiliationBSRC Alexander Fleming
Genetic informationCre-mediated recombination removed exon 4 of the Setd7 gene from the floxed Setd7tm1Ital allele.
Phenotypic informationHomozygous:
No overt phenotype

Heterozygous:
No overt phenotype
References
  • SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis.;Elkouris Maximilianos, Kontaki Haroula, Stavropoulos Athanasios, Antonoglou Anastasia, Nikolaou Kostas C, Samiotaki Martina, Szantai Eszter, Saviolaki Dimitra, Brown Peter J, Sideras Paschalis, Panayotou George, Talianidis Iannis, ;2016;Cell reports;15;2733-44; 27292644
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreB.S.R.C. Alexander Fleming, Vari, Greece
Animals used for archivinghomozygous CBA x C57BL/6, wild-type (C57BL/6 x CBA)F1
Stage of embryos2-cell

Disease and phenotype information

MGI phenotypes (allele matching)
  • abnormal lung morphology / MGI
  • abnormal lung compliance / MGI
  • decreased susceptibility to injury / MGI
  • abnormal protein level / MGI
  • decreased physiological sensitivity to xenobiotic / MGI
  • abnormal extracellular matrix morphology / MGI

Literature references

  • SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis.;Elkouris Maximilianos, Kontaki Haroula, Stavropoulos Athanasios, Antonoglou Anastasia, Nikolaou Kostas C, Samiotaki Martina, Szantai Eszter, Saviolaki Dimitra, Brown Peter J, Sideras Paschalis, Panayotou George, Talianidis Iannis, ;2016;Cell reports;15;2733-44; 27292644

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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