STOCK Dll1tm11.1Gos/Biat

Status

Available to order

EMMA IDEM:10390
International strain nameSTOCK Dll1tm11.1Gos/Biat
Alternative nameDll1EGF3m
Strain typeTargeted Mutant Strains : Knock-in
Allele/Transgene symbolDll1tm11.1Gos,
Gene/Transgene symbolDll1

Information from provider

ProviderAchim Gossler
Provider affiliationMedizinische Hochschule Hannover
Genetic informationKnock in of a Dll1 mini gene with mutated EGF3 into Dll1 locus.
Phenotypic informationHomozygous:
EGF3m lethal E18.5 massive skeletal defects.

Heterozygous:
heterozygous normal
Breeding historyFrom isogenic 129ImJ three generations on CD1, then kept on this mixed background.
References
  • Context-Dependent Sensitivity to Mutations Disrupting the Structural Integrity of Individual EGF Repeats in the Mouse Notch Ligand DLL1.;Schuster-Gossler Karin, Cordes Ralf, Müller Julia, Geffers Insa, Delany-Heiken Patricia, Taft Manuel, Preller Matthias, Gossler Achim, ;2016;Genetics;202;1119-33; 26801181
Homozygous fertileno
Homozygous viableno
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreUniversity of Veterinary Medicine, Vienna, Austria

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

Literature references

  • Context-Dependent Sensitivity to Mutations Disrupting the Structural Integrity of Individual EGF Repeats in the Mouse Notch Ligand DLL1.;Schuster-Gossler Karin, Cordes Ralf, Müller Julia, Geffers Insa, Delany-Heiken Patricia, Taft Manuel, Preller Matthias, Gossler Achim, ;2016;Genetics;202;1119-33; 26801181

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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