STOCK Tg(Tubb5-EGFP)1Dak/Biat
| Status | Available to order |
| EMMA ID | EM:10544 |
| International strain name | STOCK Tg(Tubb5-EGFP)1Dak/Biat |
| Alternative name | Tubb5 GFP / Kermit |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Tubb5-EGFP)1Dak |
| Gene/Transgene symbol | Tg(Tubb5-EGFP)1Dak |
Information from provider
| Provider | David Keays |
| Provider affiliation | Keays Group, Institute of Molecular Pathology |
| Genetic information | A Bacterial Artificial Chromosome (BAC; RP24-330C1) containing the Tubb5 gene was genetically modified to contain enhanced green fluorescent protein (EGFP) in the Tubb5 locus. |
| Phenotypic information | Homozygous:Only heterozygous have been analysed so far.Heterozygous:The mouse line drives EGFP from the endogenous Tubb5 promoter to determine which cell types express Tubb5. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | yes |
Information from EMMA
| Archiving centre | University of Veterinary Medicine, Vienna, Austria |
| Animals used for archiving | heterozygous C57BL/6N |
Literature references
- Mutations in the β-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities.;Breuss Martin, Heng Julian Ik-Tsen, Poirier Karine, Tian Guoling, Jaglin Xavier Hubert, Qu Zhengdong, Braun Andreas, Gstrein Thomas, Ngo Linh, Haas Matilda, Bahi-Buisson Nadia, Moutard Marie-Laure, Passemard Sandrine, Verloes Alain, Gressens Pierre, Xie Yunli, Robson Kathryn J H, Rani Deepa Selvi, Thangaraj Kumarasamy, Clausen Tim, Chelly Jamel, Cowan Nicholas Justin, Keays David Anthony, ;2012;Cell reports;2;1554-62; 23246003