- decreased body length / IMPC
- male infertility / IMPC
- decreased lean body mass / IMPC
- increased eosinophil cell number / IMPC
- increased effector memory CD4-positive, alpha-beta T cell number / IMPC
- increased or absent threshold for auditory brainstem response / IMPC
- decreased dendritic epidermal T cell number / IMPC
C57BL/6N-Mkrn2tm1b(KOMP)Wtsi/WtsiPh
Status | Available to order |
EMMA ID | EM:10680 |
International strain name | C57BL/6N-Mkrn2tm1b(KOMP)Wtsi/WtsiPh |
Alternative name | EPD0748_1_C12 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Mkrn2tm1b(KOMP)Wtsi, |
Gene/Transgene symbol | Mkrn2 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from KOMP ES clone EPD0748_1_C12. For further details on the construction of this clone see the page at the IMPC portal. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele using a cell permeable HTN-Cre as described in doi:10.1007/s11248-013-9764-x. Click here for more information on KOMP final vectors. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Disease and phenotype information
IMPC phenotypes (allele matching)
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