B6N.129S5(B6J)-Galr2Gt(OST105469)Lex/Biat
Status | Available to order |
EMMA ID | EM:11615 |
International strain name | B6N.129S5(B6J)-Galr2Gt(OST105469)Lex/Biat |
Alternative name | B6N-Galr2 |
Strain type | Gene-trap |
Allele/Transgene symbol | Galr2Gt(OST105469)Lex, |
Gene/Transgene symbol | Galr2 |
Information from provider
Provider | Barbara Kofler |
Provider affiliation | Research Program for Receptor Biochemistry and Tumor Metabolism, Department of Pediatrics, University Hospital Salzburg, Paracelsus Medical University |
Genetic information | Mice deficient for the GAL2-R gene were generated and licensed from Lexicon Genetics. The 5.17-kb gene-trap vector VICTR48 (viral construct for trapping) was inserted within the single intron of the murine Galr2 gene in a 129/SvEvBrd embryonic stem (ES) cell line clone (Zambrowicz et al. 2003). This Omnibank clone (OST105469; http://www.lexicon-genetics.com/discovery/omnibank.html) was used to obtain germ-line transmission of the disrupted Galr2 allele. The mouse line was first backcrossed onto the C57BL/6J background for at least 10 generations (Einstein et al., 2013) and then onto the C57BL/6N background for 4 generations (C57BL/6N genetic background was analyzed by Charles River). The mouse line is maintained on this background. |
Phenotypic information | Homozygous:No phenotypes detected; described phenotypes of founder line: http://www.informatics.jax.org/allele/allgenoviews/MGI:3530476Heterozygous:No phenotypes detected. |
Breeding history | The original mouse line (C57BL/6J × 129/SvEvBrd background) was backcrossed onto the C57BL/6J background for at least 10 generations (Einstein et al., 2013) and then backcrossed onto the C57BL/6N background for 4 generations. The mouse line is kept on this background. |
References | None available |
Homozygous fertile | yes |
Homozygous viable | yes |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | University of Veterinary Medicine, Vienna, Austria |
Animals used for archiving | homozygous Other (please specify below) |
Disease and phenotype information
MGI phenotypes (allele matching)
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