C57BL/6N-Lmnb1tm1c(EUCOMM)Wtsi/WtsiH
Status | Available to order |
EMMA ID | EM:10615 |
International strain name | C57BL/6N-Lmnb1tm1c(EUCOMM)Wtsi/WtsiH |
Alternative name | EPD0070_1_G07 |
Strain type | Targeted Mutant Strains : Targeted Conditional |
Allele/Transgene symbol | Lmnb1tm1c(EUCOMM)Wtsi |
Gene/Transgene symbol | Lmnb1 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This line originates from EUCOMM ES clone EPD0070_1_G07, after breeding with a Flp recombinase deleter line to convert the original targeted allele tm1a (knock-out first allele) into a conditional allele tm1c. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Animals used for archiving | heterozygous C57BL/6NTac |
Breeding at archiving centre | This mutation was generated on a coisogenic C57BL/6NTac background |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal dominant primary microcephaly / Orphanet_2514
- Adult-onset autosomal dominant leukodystrophy / Orphanet_99027
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