B6(Cg)-Atm1Brd Hdctm1c(EUCOMM)Hmgu/Kctt
| Status | Available to order |
| EMMA ID | EM:10674 |
| International strain name | B6(Cg)-Atm1Brd Hdctm1c(EUCOMM)Hmgu/Kctt |
| Alternative name | Hdctm1c(EUCOMM)Hmgu |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Hdctm1c(EUCOMM)Hmgu |
| Gene/Transgene symbol | Hdc |
Information from provider
| Provider | Olov Andersson |
| Provider affiliation | Cell and Molecular Biology, Karolinska Institutet |
| Additional owner | see attached MTA from EUCOMM |
| Genetic information | Hdc conditional tm1c allele generated by the following ES cells: Hdctm1a(EUCOMM)Hmgu, clone line JM8A3.N1. The generated mice were then crossed with the B6.Cg-Tg(ACTFLP-L)Dym flp recombinase-deleter strain, which was backcrossed on a C57BL/6J background (N11). We want to freeze down the tm1c allele after crossing with flp-deleter strain. |
| Phenotypic information | Homozygous:None. The floxed Hdc line was crossed with Pdx1-cre (pancreatic cre recombinase driver) and no pancreatic phenotype was detected. Heterozygous:None. The floxed Hdc line was crossed with Pdx1-cre (pancreatic cre recombinase driver) and no pancreatic phenotype was detected. |
| Breeding history | Originally C57BL/6N and then maintained on C57BL/6J. |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
| Animals used for archiving | heterozygous C57BL/6N |