C57BL/6-Tg(Hoxb8-flpo)11Oki/Kctt
| Status | Available to order |
| EMMA ID | EM:11094 |
| International strain name | C57BL/6-Tg(Hoxb8-flpo)11Oki/Kctt |
| Alternative name | Hoxb8-FlipO |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Hoxb8-flpo)11Oki, |
| Gene/Transgene symbol | Tg(Hoxb8-flpo)11Oki |
Information from provider
| Provider | Ole Kiehn |
| Provider affiliation | Neuroscience, Karolinska Institutet |
| Genetic information | A construct containing Hoxb8 upstream sequences, a FlipO recombinase cassette, and a bovine poly(A) sequence inserted in-frame downstream of the Hoxb8 ATG site. Fertilized early-stage C57BL/6J oocytes were injected with the linearized construct, and two founders were obtained and mated to generate transgenic lines. One of them, F11, exhibited the expected expression pattern of Hoxb8 at P0. |
| Phenotypic information | Homozygous:Not known, not tested.Heterozygous:No change in phenotype. Heterozygous mice behave like wild-type mice. |
| Breeding history | Strain has been kept C57BL/6. The strain has always been kept heterozygous and mostly back-crossed with wild-type siblings. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
| Animals used for archiving | heterozygous C57BL/6J |