B6.C(129)-Tg(CMV-cre)1Cgn/CgnCnrm

Status

Available to order

EMMA IDEM:01149
International strain nameB6.C(129)-Tg(CMV-cre)1Cgn/CgnCnrm
Alternative nameB6.129-Cre-Deleter
Strain typeTransgenic Strains
Allele/Transgene symbolTg(CMV-cre)1Cgn,
Gene/Transgene symbolTg(CMV-cre)1Cgn

Information from provider

ProviderKlaus Rajewsky
Provider affiliationCBR Institute for Biomedical Research, Immune Disease Institute
Genetic informationOriginal transgene construct for the expression of cre recombinase under the control of a human cytomegalovirus (CMV) promoter, active in most mouse cells and tissues.
Phenotypic informationOriginal cre recombinase-expressing transgenic mouse strain for the ubiquitous deletion in vivo ("deleter strain") of loxP-flanked gene segments.
Breeding historyBackcrossed to 129 (more than 5 generations) then backcrossed to C57BL/6 (7-8 generations)
References
  • A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells.;Schwenk F, Baron U, Rajewsky K, ;1995;Nucleic acids research;23;5080-1; 8559668

Information from EMMA

Archiving centreCNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy
Animals used for archivingheterozygous C57BL/6, wild-type C57BL/6
Stage of embryos8-cell

Literature references

  • A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells.;Schwenk F, Baron U, Rajewsky K, ;1995;Nucleic acids research;23;5080-1; 8559668
  • Liver-derived ketone bodies are necessary for food anticipation.;Chavan Rohit, Feillet Céline, Costa Sara S Fonseca, Delorme James E, Okabe Takashi, Ripperger Jürgen A, Albrecht Urs, ;2016;Nature communications;7;10580; 26838474

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Other EMMA strains

Not found what you were looking for? Search here for other strains available from EMMA.


Search
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).