129-Kiss1tm2(cre/GFP)Coll/H
Status | Available to order |
EMMA ID | EM:11714 |
International strain name | 129-Kiss1tm2(cre/GFP)Coll/H |
Alternative name | Kiss1-tm2(cre/GFP)Coll |
Strain type | Targeted Mutant Strains : Knock-in |
Allele/Transgene symbol | Kiss1tm2(cre/GFP)Coll, |
Gene/Transgene symbol | Kiss1 |
Information from provider
Provider | William Colledge |
Provider affiliation | PDN, University of Cambridge |
Genetic information | Targeted disruption of Kiss1 gene with insertion of a fused CRE:GFP, the expression of which is driven from the Kiss1 promoter. |
Phenotypic information | Homozygous:Male and female sterilityHeterozygous:No obvious phenotype |
Breeding history | Chimaeras from 129S/SvEv ES cells were crossed with 129 mice from Taconic. |
References | None available |
Homozygous fertile | no |
Homozygous viable | yes |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Normosmic congenital hypogonadotropic hypogonadism / Orphanet_432
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