B6;D2-Tg(Ntrk2-cre/ERT2)#Phep/Cnrm
| Status | Available to order |
| EMMA ID | EM:11775 |
| International strain name | B6;D2-Tg(Ntrk2-cre/ERT2)#Phep/Cnrm |
| Alternative name | TrkB-CreERT2 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Ntrk2-cre/ERT2)#Phep |
| Gene/Transgene symbol | Tg(Ntrk2-cre/ERT2)#Phep |
Information from provider
| Provider | Paul Heppenstall |
| Provider affiliation | EMBL |
| Genetic information | Bacterial artificial chromosome (BAC) containing the TrkB mouse locus. A cassette containing a modified CreERT2-pA-Frt-Ampicillin-Frt construct was inserted into the ATG of BAC-TrkB, deleting entire coding part of exon 2 to avoid overexpression of TrkB. |
| Phenotypic information | Homozygous:No overt phenotypeHeterozygous:No overt phenotype |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons.;Dhandapani Rahul, Arokiaraj Cynthia Mary, Taberner Francisco J, Pacifico Paola, Raja Sruthi, Nocchi Linda, Portulano Carla, Franciosa Federica, Maffei Mariano, Hussain Ahmad Fawzi, de Castro Reis Fernanda, Reymond Luc, Perlas Emerald, Garcovich Simone, Barth Stefan, Johnsson Kai, Lechner Stefan G, Heppenstall Paul A, ;2018;Nature communications;9;1640; 29691410