STOCK Egr2tm2(cre)Pch/Orl
Status | Available to order |
EMMA ID | EM:11829 |
International strain name | STOCK Egr2tm2(cre)Pch/Orl |
Alternative name | Krox20 cre |
Strain type | Targeted Mutant Strains : Knock-in |
Allele/Transgene symbol | Egr2tm2(cre)Pch , |
Gene/Transgene symbol | Egr2 |
Information from provider
Provider | Carole Desmarquet-Trin-Dinh |
Provider affiliation | Equipe Developpement du Systeme Nerveux IBENS, INSERM U 1024, CNRS UMR 8197, Ecole Normale Superieure |
Genetic information | Knock-in insertion of cre gene in Krox20/Egr2 locus |
Phenotypic information | Homozygous:Nothing to reportHeterozygous:Nothing to report |
References |
|
Homozygous fertile | yes |
Homozygous viable | yes |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Animals used for archiving | heterozygous (C57BL/6 x DBA/2)F1, wild-type (C57BL/6 x DBA/2)F1 |
Stage of embryos | 2-cell |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Dejerine-Sottas syndrome / Orphanet_64748
- Charcot-Marie-Tooth disease type 1D / Orphanet_101084
- Charcot-Marie-Tooth disease type 4E / Orphanet_99951
Literature references
- Expression pattern of a Krox-20/Cre knock-in allele in the developing hindbrain, bones, and peripheral nervous system.;Voiculescu O, Charnay P, Schneider-Maunoury S, ;2000;Genesis (New York, N.Y. : 2000);26;123-6; 10686605
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