B6(Cg)-Tg(Th-tTA2syn)1Ekra/H
| Status | Available to order |
| EMMA ID | EM:11952 |
| International strain name | B6(Cg)-Tg(Th-tTA2syn)1Ekra/H |
| Alternative name | C57BL/6J-Tg(TH-tTA2syn)1EKra |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Unknown at present |
| Gene/Transgene symbol | TH-tTA |
Information from provider
| Provider | Edgar Kramer |
| Provider affiliation | Biomedical Research, Institute of Translational and Stratified Medicine, Peninsula Schools of Medicine and Dentistry, University of Plymouth |
| Genetic information | tTA2syn under the control of the mouse Th promoter (8.9kbp). |
| Phenotypic information | Homozygous:not doneHeterozygous:mTH-tTA OFF#2096 can be used to induced tTA expression in catecholaminergic neurons expressing tyrosine hydroxylase; tTA can induce gene expression in the absence of tetracycline/doxycycline (Tillack et al., 2015). |
| Breeding history | Crossed with LC1 mice (Schoenig et al., 2002), ROSA26R mice (Soriano, 1999) and Ret floxed mice (Kramer et al., 2006). |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |