C57BL/6-Dbhtm1a(EUCOMM)Wtsi/Cnbc
| Status | Available to order |
| EMMA ID | EM:12233 |
| International strain name | C57BL/6-Dbhtm1a(EUCOMM)Wtsi/Cnbc |
| Alternative name | Dbhtm1a(EUCOMM)Wtsi |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Dbhtm1a(EUCOMM)Wtsi, |
| Gene/Transgene symbol | Dbh |
Information from provider
| Provider | Miguel Soares |
| Provider affiliation | Biomedicine, LAIMM - Faculty of Medicine of Porto, Portugal |
| Genetic information | Gene targeted: Dbh (dopamine beta hydroxylase; MGI:94864). Knockout first mice (KOMP tm1a allele; reporter-tagged insertion with conditional potential). |
| Phenotypic information | Homozygous:http://www.informatics.jax.org/marker/phenotypes/MGI:94864Heterozygous:no abnormal phenotype detected |
| Breeding history | 10+ generations. First backcrosses (not with parents but with unrelated C57BL/6J animals), then intercrosses (avoided consanguinity). |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | no |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | heterozygous C57BL/6J |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Dopamine beta-hydroxylase deficiency / Orphanet_230