STOCK Gt(ROSA)26Sortm1(CAG-GCaMP5)Khps/H
| Status | Available to order |
| EMMA ID | EM:12659 |
| International strain name | STOCK Gt(ROSA)26Sortm1(CAG-GCaMP5)Khps/H |
| Alternative name | Tg(ROSA26-LSL-SyGCaMP-WPRE)L4 |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Gt(ROSA)26Sortm1(CAG-GCaMP5)Khps, |
| Gene/Transgene symbol | Gt(ROSA)26Sor |
Information from provider
| Provider | Kate Hampden-Smith |
| Provider affiliation | University of Sussex |
| Additional owner | Rachel Wong, University of Washington, University of Washington, Department of Biological Structure, Seattle, USA |
| Genetic information | SyGCaMP5-L4 mice are a cre recombinase-dependent, fluorescent, calcium-indicator tool strain. Cross with cre-expressing lines to remove loxP-flanked stop cassette upstream of the fluorescent calcium reporter to induce selective expression in terminals of cre-positive cells. |
| Phenotypic information | Homozygous:No phenotype in absence of cre recombinase. Following exposure to cre recombinase, SyGCaMP5 expression is detected in the cre-expressing tissues. Mice homozygous for the conditional allele are viable and fertile. Heterozygous:No phenotype in absence of cre recombinase. Following exposure to cre recombinase, SyGCaMP5 expression is detected in the cre-expressing tissues. Mice heterozygous for the conditional allele are viable and fertile. |
| Breeding history | Bred with C57BL/6 mice to produce heterozygous strain, but also het x het pairing tested and homozygous mice are still viable. |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |