B6;129-Tmsb4xtm1Prri/H

Status

Available to order

EMMA IDEM:01301
International strain nameB6;129-Tmsb4xtm1Prri/H
Alternative nameTmsb4x
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolTmsb4xtm1Prri,
Gene/Transgene symbolTmsb4x

Information from provider

ProviderMartin Turner
Provider affiliationBabraham Institute
Genetic informationIn this knock-out line B-lymphocyte development is impaired.
Phenotypic informationImpairment of B-lymphocyte development and immune deficient.
References
  • Essential role for thymosin β4 in regulating vascular smooth muscle cell development and vessel wall stability.;Rossdeutsch Alex, Smart Nicola, Dubé Karina N, Turner Martin, Riley Paul R, ;2012;Circulation research;111;e89-102; 22723298

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (allele matching)
  • abnormal blood vessel morphology / MGI
  • internal hemorrhage / MGI
  • intracranial hemorrhage / MGI
  • thin myocardium / MGI
  • abnormal arteriole morphology / MGI
  • hemopericardium / MGI
  • vision/eye phenotype / MGI
  • heart hemorrhage / MGI
  • embryonic lethality during organogenesis, incomplete penetrance / MGI
  • abnormal vascular smooth muscle development / MGI

Literature references

  • Essential role for thymosin β4 in regulating vascular smooth muscle cell development and vessel wall stability.;Rossdeutsch Alex, Smart Nicola, Dubé Karina N, Turner Martin, Riley Paul R, ;2012;Circulation research;111;e89-102; 22723298

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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