B6.Cg-Tg(Scgb1a1-cre)1Vart/Flmg
| Status | Available to order |
| EMMA ID | EM:13121 |
| International strain name | B6.Cg-Tg(Scgb1a1-cre)1Vart/Flmg |
| Alternative name | B6-Tg(Scgb1a1-cre)1Vart/Flmg |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Scgb1a1-cre)1Vart, |
| Gene/Transgene symbol | Tg(Scgb1a1-cre)1Vart |
Information from provider
| Provider | Vassilis Aidinis |
| Provider affiliation | BioInnovation, BSRC |
| Genetic information | This transgene contains the cDNA encoding cre recombinase under control of the promoter from the rat secretoglobin, family 1A, member 1 gene (Clara cell 10 kD or CC10), which directs expression in Clara cells of the pulmonary epithelium. |
| Phenotypic information | Homozygous:No overt phenotypeHeterozygous:No overt phenotype |
| Breeding history | This mouse was generated in a B6;CBA mixed background and has now been back-crossed into pure C57BL/6 background. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | B.S.R.C. Alexander Fleming, Vari, Greece |
| Animals used for archiving | heterozygous C57BL/6J, wild-type C57BL/6J |
| Stage of embryos | Morula |
Literature references
- Pulmonary autotaxin expression contributes to the pathogenesis of pulmonary fibrosis.;Oikonomou Nikos, Mouratis Marios-Angelos, Tzouvelekis Argyris, Kaffe Eleanna, Valavanis Christos, Vilaras George, Karameris Andreas, Prestwich Glenn D, Bouros Demosthenes, Aidinis Vassilis, ;2012;American journal of respiratory cell and molecular biology;47;566-74; 22744859