C57BL/6-Tg(rtetR-tetO-cre)40Mhz/Orl

Status	Available to order
EMMA ID	EM:01372
International strain name	C57BL/6-Tg(rtetR-tetO-cre)40Mhz/Orl
Alternative name	MeuCre40
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(rtetR-tetO-cre)40Mhz,
Gene/Transgene symbol	Tg(rtetR-tetO-cre)40Mhz

Information from provider

Provider	Martin HOLZENBERGER
Provider affiliation	Université Pierre et Marie Curie, INSERM, U938, Hôpital Saint Antoine
Genetic information	Construct: a bidirectional CMV minimal promoter expressing wild-type cre recombinase cDNA on one side and rtTA on the other side. Although originally designed as auto-inducible by tetracycline, this transgenic strain is constitutively activated during early embryogenesis and can produce partial and mosaic loxP recombination from tri-lox alleles.
Phenotypic information	None
References	Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles.;Leneuve Patricia, Colnot Sabine, Hamard Ghislaine, Francis Fiona, Niwa-Kawakita Michiko, Giovannini Marco, Holzenberger Martin, ;2003;Nucleic acids research;31;e21; 12595570

Information from EMMA

Archiving centre	Institut de Transgenose, INTRAGENE, Orléans, France

Literature references

Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles.;Leneuve Patricia, Colnot Sabine, Hamard Ghislaine, Francis Fiona, Niwa-Kawakita Michiko, Giovannini Marco, Holzenberger Martin, ;2003;Nucleic acids research;31;e21; 12595570

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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