C57BL/6-Tg(Prox1-cre/ERT2)1Tmak/H

Status	Available to order
EMMA ID	EM:13737
International strain name	C57BL/6-Tg(Prox1-cre/ERT2)1Tmak/H
Alternative name	Prox1-CreERT2
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(Prox1-cre/ERT2)1Tmak,
Gene/Transgene symbol	Tg(Prox1-cre/ERT2)1Tmak

Information from provider

Provider	Taija Makinen
Provider affiliation	Lymphatic Development Laboratory, Uppsala University
Genetic information	A cDNA encoding tamoxifen inducible Cre recombinase (CreERT2) followed by SV40 polyadenylation signal was introduced into the start codon of Prox1 in BAC clone RP23-190F21 using homologous recombination in bacteria.
Phenotypic information	Homozygous: Phenotypically normal Heterozygous: Phenotypically normal
Breeding history	Congenic
References	Genes regulating lymphangiogenesis control venous valve formation and maintenance in mice.;Bazigou Eleni, Lyons Oliver T A, Smith Alberto, Venn Graham E, Cope Celia, Brown Nigel A, Makinen Taija, ;2011;The Journal of clinical investigation;121;2984-92; 21765212
Homozygous fertile	yes
Homozygous viable	yes
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Literature references

Genes regulating lymphangiogenesis control venous valve formation and maintenance in mice.;Bazigou Eleni, Lyons Oliver T A, Smith Alberto, Venn Graham E, Cope Celia, Brown Nigel A, Makinen Taija, ;2011;The Journal of clinical investigation;121;2984-92; 21765212

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*
Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
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Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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