| Status | Available to order |
| EMMA ID | EM:01398 |
| International strain name | NOD.B6-(D17Mit16-D17Mit36)/GhjCnrm |
| Alternative name | NOD.B6-C17(R2) |
| Strain type | Other |
| Allele/Transgene symbol | H2b, |
| Gene/Transgene symbol | H2 |
| Provider | Henri-Jean Garchon |
| Provider affiliation | ER70 CNRS et Unite 125 Inserm |
| Genetic information | NOD congenic strain with the H2 complex from C57BL/6. The R2 interval includes the Idd1 but excludes the Idd16 locus. |
| Phenotypic information | This line and the related lines, consomic, congenic and subcongenic for chromosome 17 and fragments of this chromosome, were derived to thoroughly investigate the role of the major histocompatibility complex (MHC) and MHC-linked genes in autoimmune predisposition, notably including type I diabetes (Idd1 and Idd16) loci and chronic autoimmune thyroiditis (Ceat1) locus, on the non-obese diabetic (NOD) background. The R2 line is completely protected against type 1 diabetes. |
| Breeding history | 20 generations of backcrosses followed by sister-brother matings. Selection of subcongenics by additional backcrosses. |
| References |
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| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
