B6NCrl.Cg-Gt(ROSA)26Sortm1.1(CAG-AOX)Htj/Ieg

Status

Available to order

EMMA IDEM:14847
International strain nameB6NCrl.Cg-Gt(ROSA)26Sortm1.1(CAG-AOX)Htj/Ieg
Alternative nameAOXRosa26
Strain typeTargeted Mutant Strains : Knock-in
Allele/Transgene symbolGt(ROSA)26Sortm1.1(CAG-AOX)Htj,
Gene/Transgene symbolGt(ROSA)26Sor

Information from provider

ProviderHoward Jacobs
Provider affiliationFaculty of Medicine and Health Technology, Tampere University
Additional owneroriginal mouse line belongs to Marten Szibor, from the same institution as the strain provider
Genetic informationAOXrosa26_tg_het
Phenotypic informationHomozygous:
Homozygous mice were not investigated

Heterozygous:
None
Breeding historyAOXRosa26_tg_het on a C57BL/6J background was backcrossed to C57BL/6NCrl over 7 generations
References
  • Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology.;Szibor Marten, Dhandapani Praveen K, Dufour Eric, Holmström Kira M, Zhuang Yuan, Salwig Isabelle, Wittig Ilka, Heidler Juliana, Gizatullina Zemfira, Gainutdinov Timur, null null, Fuchs Helmut, Gailus-Durner Valérie, de Angelis Martin Hrabě, Nandania Jatin, Velagapudi Vidya, Wietelmann Astrid, Rustin Pierre, Gellerich Frank N, Jacobs Howard T, Braun Thomas, ;2017;Disease models & mechanisms;10;163-171; 28067626
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archivingheterozygous C57BL/6N

Literature references

  • Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology.;Szibor Marten, Dhandapani Praveen K, Dufour Eric, Holmström Kira M, Zhuang Yuan, Salwig Isabelle, Wittig Ilka, Heidler Juliana, Gizatullina Zemfira, Gainutdinov Timur, null null, Fuchs Helmut, Gailus-Durner Valérie, de Angelis Martin Hrabě, Nandania Jatin, Velagapudi Vidya, Wietelmann Astrid, Rustin Pierre, Gellerich Frank N, Jacobs Howard T, Braun Thomas, ;2017;Disease models & mechanisms;10;163-171; 28067626

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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