B6;D2-Tg(Ttr-cre/Esr1*)1Vco/Orl
| Status | Available to order |
| EMMA ID | EM:01713 |
| International strain name | B6;D2-Tg(Ttr-cre/Esr1*)1Vco/Orl |
| Alternative name | TTR-Cre ind |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Ttr-cre/Esr1*)1Vco, |
| Gene/Transgene symbol | Tg(Ttr-cre/Esr1*)1Vco |
Information from provider
| Provider | Mireille Vasseur-Cognet |
| Provider affiliation | Institut Cochin, INSERM U567, Faculté de Cochin, GDPM |
| Genetic information | Gene fusion of the cre recombinase and mouse estrogen receptor hormone-binding domain coding sequences, under the control of a mouse transthyretin promoter. |
| Phenotypic information | No defects. |
| Breeding history | Transgenic mice have always been bred as heterozygotes with wild-type mice. |
| References |
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Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6J, wild-type C57BL/6J |
| Breeding at archiving centre | Males are transgenic: some of them are perhaps homozygous but they can be discriminated by PCR. |
Literature references
- A tamoxifen-inducible chimeric Cre recombinase specifically effective in the fetal and adult mouse liver.;Tannour-Louet Mounia, Porteu Arlette, Vaulont Sophie, Kahn Axel, Vasseur-Cognet Mireille, ;2002;Hepatology (Baltimore, Md.);35;1072-81; 11981757
- Loss of the anaphase-promoting complex in quiescent cells causes unscheduled hepatocyte proliferation.;Wirth Karin G, Ricci Romeo, Giménez-Abián Juan F, Taghybeeglu Shahryar, Kudo Nobuaki R, Jochum Wolfram, Vasseur-Cognet Mireille, Nasmyth Kim, ;2004;Genes & development;18;88-98; 14724179