B6J;129S1-Capn5tm1Nde/H

Status

Available to order

EMMA IDEM:01718
International strain nameB6J;129S1-Capn5tm1Nde/H
Alternative nameCapn5
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolCapn5tm1Nde,
Gene/Transgene symbolCapn5

Information from provider

ProviderNeil Dear
Provider affiliationMRC Mammalian Genetics Unit
Genetic informationAn IRES-lacZ-neomycin cassette was inserted into exon 4 of the Capn5 gene by homologous recombination.
Phenotypic informationCAPN5 is a protease expressed in T cells. The Capn5 gene has been inactivated in this mouse strain.
References
  • Capn5 is expressed in a subset of T cells and is dispensable for development.;Franz Tanna, Winckler Lara, Boehm Thomas, Dear T Neil, ;2004;Molecular and cellular biology;24;1649-54; 14749380

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

    • Autosomal dominant neovascular inflammatory vitreoretinopathy / Orphanet_329211
MGI phenotypes (allele matching)
  • decreased body size / MGI
  • premature death / MGI
  • immune system phenotype / MGI
  • postnatal lethality, incomplete penetrance / MGI

Literature references

  • Capn5 is expressed in a subset of T cells and is dispensable for development.;Franz Tanna, Winckler Lara, Boehm Thomas, Dear T Neil, ;2004;Molecular and cellular biology;24;1649-54; 14749380

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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