| Status | Available to order |
| EMMA ID | EM:01789 |
| International strain name | STOCK Axin2tm1Wbm/Ieg |
| Alternative name | Conductin (Axin2)-lacZ |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Axin2tm1Wbm, |
| Gene/Transgene symbol | Axin2 |
| Provider | Boris Jerchow |
| Provider affiliation | Max-Delbrueck-Center for Molecular Medicine - HGF |
| Genetic information | Axin2 null mutation. Knock-in of a NLS-lacZ cassette in frame with the ATG start codon of Axin2. Antisense PGK-neo cassette flanked by loxP-sites following the lacZ. Only splice acceptor and donor of first coding exon (exon 2) left. |
| Phenotypic information | Minor defect: craniosynosthosis. |
| Breeding history | Backcrossed to C57BL/6. Number of generations unknown. Currently backcrossed to C57BL/6 and mated to (C57BL/6 x DBA/2)F1 hybrids. |
| References |
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| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
MGI allele-associated human disease models
Orphanet associated rare diseases, based on orthologous gene matching
