- abnormal cochlea morphology / MGI
- abnormal stria vascularis morphology / MGI
- belly spot / MGI
- abnormal coat/hair pigmentation / MGI
- abnormal cochlear hair cell morphology / MGI
- white spotting / MGI
- head spot / MGI
- decreased eye pigmentation / MGI
- abnormal iris stromal pigmentation / MGI
- abnormal vestibular saccule morphology / MGI
- abnormal mast cell physiology / MGI
- abnormal serotonin level / MGI
- osteopetrosis / MGI
- failure of tooth eruption / MGI
- decreased mast cell number / MGI
- abnormal eye development / MGI
- microphthalmia / MGI
- absent optic nerve / MGI
- postnatal lethality / MGI
- abnormal scala media morphology / MGI
- abnormal optic stalk morphology / MGI
- abnormal optic cup morphology / MGI
- abnormal osteoclast morphology / MGI
- increased osteoclast cell number / MGI
- abnormal optic choroid morphology / MGI
- abnormal ciliary body morphology / MGI
- abnormal retinal pigmentation / MGI
- absent coat pigmentation / MGI
- eyelids fail to open / MGI
- abnormal posterior eye segment morphology / MGI
- abnormal retinal pigment epithelium morphology / MGI
- coloboma / MGI
- abnormal skeleton morphology / MGI
- abnormal retinal neuronal layer morphology / MGI
- decreased survivor rate / MGI
- decreased body size / MGI
- absent eye pigmentation / MGI
- absent skin pigmentation / MGI
- hypopigmentation / MGI
- vision/eye phenotype / MGI
MI/HgDstIeg
Status | Available to order |
EMMA ID | EM:00198 |
International strain name | MI/HgDstIeg |
Alternative name | Hertwig`s microphthalmia |
Strain type | Induced Mutant Strains : Radiation-induced |
Allele/Transgene symbol | MitfMi, |
Gene/Transgene symbol | Mitf |
Information from provider
Provider | Dietmar Schlote |
Provider affiliation | Martin-Luther University, Halle/Wittenberg |
Phenotypic information | Microphthalmia. heterozygous mice exhibit less iris pigment; homozygous mice are devoid of iris pigment |
References | None available |
Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
MGI allele-associated human disease models
Orphanet associated rare diseases, based on orthologous gene matching
- Tietz syndrome / Orphanet_42665
- Ocular albinism with congenital sensorineural deafness / Orphanet_352740
- Waardenburg syndrome type 2 / Orphanet_895
- Waardenburg-Shah syndrome / Orphanet_897
MGI phenotypes (allele matching)
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