MI/HgDstIeg

Status

Available to order

EMMA IDEM:00198
International strain nameMI/HgDstIeg
Alternative nameHertwig`s microphthalmia
Strain typeInduced Mutant Strains : Radiation-induced
Allele/Transgene symbolMitfMi,
Gene/Transgene symbolMitf

Information from provider

ProviderDietmar Schlote
Provider affiliationMartin-Luther University, Halle/Wittenberg
Phenotypic informationMicrophthalmia. heterozygous mice exhibit less iris pigment; homozygous mice are devoid of iris pigment
ReferencesNone available

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany

Disease and phenotype information

MGI allele-associated human disease models

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (allele matching)
  • abnormal cochlea morphology / MGI
  • abnormal stria vascularis morphology / MGI
  • belly spot / MGI
  • abnormal coat/hair pigmentation / MGI
  • abnormal cochlear hair cell morphology / MGI
  • white spotting / MGI
  • head spot / MGI
  • decreased eye pigmentation / MGI
  • abnormal iris stromal pigmentation / MGI
  • abnormal vestibular saccule morphology / MGI
  • abnormal mast cell physiology / MGI
  • abnormal serotonin level / MGI
  • osteopetrosis / MGI
  • failure of tooth eruption / MGI
  • decreased mast cell number / MGI
  • abnormal eye development / MGI
  • microphthalmia / MGI
  • absent optic nerve / MGI
  • postnatal lethality / MGI
  • abnormal scala media morphology / MGI
  • abnormal optic stalk morphology / MGI
  • abnormal optic cup morphology / MGI
  • abnormal osteoclast morphology / MGI
  • increased osteoclast cell number / MGI
  • abnormal optic choroid morphology / MGI
  • abnormal ciliary body morphology / MGI
  • abnormal retinal pigmentation / MGI
  • absent coat pigmentation / MGI
  • eyelids fail to open / MGI
  • abnormal posterior eye segment morphology / MGI
  • abnormal retinal pigment epithelium morphology / MGI
  • coloboma / MGI
  • abnormal skeleton morphology / MGI
  • abnormal retinal neuronal layer morphology / MGI
  • decreased survivor rate / MGI
  • decreased body size / MGI
  • absent eye pigmentation / MGI
  • absent skin pigmentation / MGI
  • hypopigmentation / MGI
  • vision/eye phenotype / MGI

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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